Tight Alright - A Pressure-sensing Compression Device for Venous Leg Ulcer Therapy



Dr Andrew Cameron has received funding from Enterprise Ireland's Commercialisation Fund to develop Tight Alright, a pressure bandage for the treatment of venous leg ulcers. The project will be carried out in the Duffy Lab, in collaboration with Bioinnovate and the School of Medicine, NUIG.

Clinical Background

Venous leg ulcers (VLUs) stem from a pathological change in the skin and subcutaneous tissues, resulting from venous insufficiency and an associated accumulation of blood in the lower limbs. The current gold standard treatment for VLUs is graduated compression therapy (40 mmHg pressure at ankle, 20 mmHg below knee).



• 1% lifetime prevalence of VLUs in the Western world
- People aged ≥65 years is 3-4%

• 600,000 people with VLUs in the USA at any one time
- ~1.5 million people/year with treatable VLUs in USA
- 278,000 people/year with VLUs in UK


• VLU healing rates can be highly variable
- 55% to 93% healing after 12 months

• Average cost of treating a VLU in the USA is $16,000
- $10,500 for ulcers that heal (avg. healing time of 4 months)
- $34,000 for non-healing ulcers

• Total US payer burden for VLU treatment is $14.9 billion annually


• Global compression bandage market was $1.34 billion in 2016 o USA is $634 million
- Europe is $433 million

• $313 million addressable market for VLUs within the USA and Europe
- US reimbursement for below-the-knee gradient compression wraps is $94.17
- Conservative cost of similar products in Europe is $200

Clinical Problem

• Standardised pressure application is rarely achieved
- <10% of 891 healthcare providers applied correct pressure
- No benefit of professional experience

• Non-compliance impedes compression treatment
- 10%-80% non-compliance in community studies
- 6 month healing rates: 78% in compliant Vs 29% in non-compliant patients

Current Technology Limitations


Tight Alright Concept and Competetive Advantages

The first adjustable compression device with inherent pressure sensing properties, which interacts with a digital interface capable of accurately measuring and continuously monitoring sub-bandage pressure in any location during VLU treatment.



Dr Andrew Cameron
Human Biology Building Rm 1002
Discipline of Anatomy
School of Medicine
National University of Ireland Galway
University Road, Galway, Ireland

Andrew Cameron
☏ +353-91-495-2681